Sohela Shah

Program Manager Catalyst Program and InVent Fund
Catalyst
+1 628 206-4857

Sohela is a program manager at the Catalyst Program and InVent Fund teams at Innovation Ventures at UCSF. She is excited to support UCSF faculty in advancing their research projects towards technology patenting and commercialization in order to bring cutting-edge innovations out of the lab and into the world. Prior to joining Innovation Ventures, she worked on a startup project at The Production Board, a technology incubator and investment holding company in San Francisco, as the founding product manager.

Sohela earned her Ph.D. in Genetics from Tufts University- School of Biomedical Sciences in Boston and did postdoctoral training in rare disease genetics at the University of California San Francisco. After her postdoc, she joined Memorial Sloan Kettering Cancer Center as a Niehaus Scholar to continue her research in clinical genetics and genomics. Following her research fellowship in New York, she led the development of NGS data interpretation and reporting software for genetic test results at Ingenuity Systems (acquired by QIAGEN) and Invitae Corp.

Publications: 

Working toward precision medicine: Predicting phenotypes from exomes in the Critical Assessment of Genome Interpretation (CAGI) challenges.

Human mutation

Daneshjou R, Wang Y, Bromberg Y, Bovo S, Martelli PL, Babbi G, Lena PD, Casadio R, Edwards M, Gifford D, Jones DT, Sundaram L, Bhat RR, Li X, Pal LR, Kundu K, Yin Y, Moult J, Jiang Y, Pejaver V, Pagel KA, Li B, Mooney SD, Radivojac P, Shah S, Carraro M, Gasparini A, Leonardi E, Giollo M, Ferrari C, Tosatto SCE, Bachar E, Azaria JR, Ofran Y, Unger R, Niroula A, Vihinen M, Chang B, Wang MH, Franke A, Petersen BS, Pirooznia M, Zandi P, McCombie R, Potash JB, Altman RB, Klein TE, Hoskins RA, Repo S, Brenner SE, Morgan AA

Lessons from the CAGI-4 Hopkins clinical panel challenge.

Human mutation

Chandonia JM, Adhikari A, Carraro M, Chhibber A, Cutting GR, Fu Y, Gasparini A, Jones DT, Kramer A, Kundu K, Lam HYK, Leonardi E, Moult J, Pal LR, Searls DB, Shah S, Sunyaev S, Tosatto SCE, Yin Y, Buckley BA

Evaluating the association of multiple single nucleotide polymorphisms with response to gemcitabine and platinum combination chemotherapy in urothelial carcinoma of the bladder
.

International journal of clinical pharmacology and therapeutics

Alanee SR, Shah S, Zabor EC, Vijai J, Ostrovnaya I, Garcia-Grossman IR, Pendse DV, Littman J, Regazzi AM, Offit K, Bajorin DF

Better bioinformatics will help labs manage genetic testing.

MLO: medical laboratory observer

Shah S

Intrahepatic Cholestasis of Pregnancy (ICP) in U.S. Latinas and Chileans: Clinical features, Ancestry Analysis, and Admixture Mapping.

PloS one

Bull LN, Hu D, Shah S, Temple L, Silva K, Huntsman S, Melgar J, Geiser MT, Sanford U, Ortiz JA, Lee RH, Kusanovic JP, Ziv E, Vargas JE

Genome Sequencing of Multiple Primary Tumors Reveals a Novel PALB2 Variant.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Schrader KA, Stratton KL, Murali R, Laitman Y, Cavallone L, Offit L, Wen YH, Thomas T, Shah S, Rau-Murthy R, Manschreck C, Salo-Mullen E, Otegbeye E, Corines M, Zhang L, Norton L, Hudis C, Klein RJ, Kauff ND, Robson M, Stadler ZK, Haber DA, Lipkin SM, Friedman E, Foulkes WD, Altshuler D, Vijai J, Offit K

Prevalence of HOXB13 mutation in a population of Ashkenazi Jewish men treated for prostate cancer.

Familial cancer

Alanee S, Shah S, Vijai J, Schrader K, Hamilton R, Rau-Murthy R, Sarrel K, Manschreck C, Eastham J, Offit K

CCBE1 mutation in two siblings, one manifesting lymphedema-cholestasis syndrome, and the other, fetal hydrops.

PloS one

Shah S, Conlin LK, Gomez L, Aagenaes Ø, Eiklid K, Knisely AS, Mennuti MT, Matthews RP, Spinner NB, Bull LN

A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia.

Nature genetics

Shah S, Schrader KA, Waanders E, Timms AE, Vijai J, Miething C, Wechsler J, Yang J, Hayes J, Klein RJ, Zhang J, Wei L, Wu G, Rusch M, Nagahawatte P, Ma J, Chen SC, Song G, Cheng J, Meyers P, Bhojwani D, Jhanwar S, Maslak P, Fleisher M, Littman J, Offit L, Rau-Murthy R, Fleischut MH, Corines M, Murali R, Gao X, Manschreck C, Kitzing T, Murty VV, Raimondi S, Kuiper RP, Simons A, Schiffman JD, Onel K, Plon SE, Wheeler D, Ritter D, Ziegler DS, Tucker K, Sutton R, Chenevix-Trench G, Li J, Huntsman DG, Hansford S, Senz J, Walsh T, Lee M, Hahn CN, Roberts K, King MC, Lo SM, Levine RL, Viale A, Socci ND, Nathanson KL, Scott HS, Daly M, Lipkin SM, Lowe SW, Downing JR, Altshuler D, Sandlund JT, Horwitz MS, Mullighan CG, Offit K

Assessment of SLX4 Mutations in Hereditary Breast Cancers.

PloS one

Shah S, Kim Y, Ostrovnaya I, Murali R, Schrader KA, Lach FP, Sarrel K, Rau-Murthy R, Hansen N, Zhang L, Kirchhoff T, Stadler Z, Robson M, Vijai J, Offit K, Smogorzewska A

Absence of loss of heterozygosity of BRCA1 in a renal tumor from a BRCA1 germline mutation carrier.

Familial cancer

Alanee S, Shah S, Murali R, Rau-Murthy R, Schrader KA, Offit K

Rare variants in XRCC2 as breast cancer susceptibility alleles.

Journal of medical genetics

Hilbers FS, Wijnen JT, Hoogerbrugge N, Oosterwijk JC, Collee MJ, Peterlongo P, Radice P, Manoukian S, Feroce I, Capra F, Couch FJ, Wang X, Guidugli L, Offit K, Shah S, Campbell IG, Thompson ER, James PA, Trainer AH, Gracia J, Benitez J, van Asperen CJ, Devilee P

Rare de novo germline copy-number variation in testicular cancer.

American journal of human genetics

Stadler ZK, Esposito D, Shah S, Vijai J, Yamrom B, Levy D, Lee YH, Kendall J, Leotta A, Ronemus M, Hansen N, Sarrel K, Rau-Murthy R, Schrader K, Kauff N, Klein RJ, Lipkin SM, Murali R, Robson M, Sheinfeld J, Feldman D, Bosl G, Norton L, Wigler M, Offit K

Strain background modifies phenotypes in the ATP8B1-deficient mouse.

PloS one

Shah S, Sanford UR, Vargas JC, Xu H, Groen A, Paulusma CC, Grenert JP, Pawlikowska L, Sen S, Elferink RP, Bull LN

Babesia microti primarily invades mature erythrocytes in mice.

Infection and immunity

Borggraefe I, Yuan J, Telford SR, Menon S, Hunter R, Shah S, Spielman A, Gelfand JA, Wortis HH, Vannier E