Amy Gryshuk, PhD

Associate Director
Office of Strategic Alliances
(716) 574-0645

Amy joined the University of California, San Francisco, as the Associate Director of the Office of Strategic Alliances for the department of Innovation Ventures in July 2022. She received her PhD in Molecular Pharmacology from the State University of New York at Buffalo – Roswell Park Cancer Institute. She has experience in designing, implementing, and maintaining tailored action plans and partnering strategies for multidisciplinary research collaborations and agreements with government, industry, academia, and philanthropy partners. 

Previously, Amy served as a Lead within the Strategic Science Engagements Office for the Physical and Life Sciences Directorate at Lawrence Livermore National Laboratory where she coordinated high-level efforts across various Department of Energy (DOE) labs and the National Cancer Institute and was recognized in 2017 by the United States Department of Energy for the Secretary’s Appreciation Award for responding to the Vice President's Cancer Moonshot. She has focused on the application of computational predictive biology in oncology, drug discovery, and neurodegenerative efforts resulting in numerous publications and external funding. 

Publications: 

An electronic health record cohort of Veterans with amyotrophic lateral sclerosis.

Amyotrophic lateral sclerosis & frontotemporal degeneration

Reimer RJ, Goncalves A, Soper B, Cadena J, Wilson JL, Gryshuk AL, Suarez P, Osborne TF, Grimes KV, Ray P

COVID-19 outcomes in patients with cancer: Findings from the University of California health system database.

Cancer medicine

Kwon DH, Cadena J, Nguyen S, Chan KHR, Soper B, Gryshuk AL, Hong JC, Ray P, Huang FW

Digital twins for predictive oncology will be a paradigm shift for precision cancer care.

Nature medicine

Hernandez-Boussard T, Macklin P, Greenspan EJ, Gryshuk AL, Stahlberg E, Syeda-Mahmood T, Shmulevich I

AI Meets Exascale Computing: Advancing Cancer Research With Large-Scale High Performance Computing.

Frontiers in oncology

Bhattacharya T, Brettin T, Doroshow JH, Evrard YA, Greenspan EJ, Gryshuk AL, Hoang TT, Lauzon CBV, Nissley D, Penberthy L, Stahlberg E, Stevens R, Streitz F, Tourassi G, Xia F, Zaki G

Emerging topics and new developments in the field: the 2012 International Breath Analysis meeting.

Journal of breath research

Davis CE, Epton M, Frank M, Gryshuk A, Kenyon NJ

Cell-phone-based platform for biomedical device development and education applications.

PloS one

Smith ZJ, Chu K, Espenson AR, Rahimzadeh M, Gryshuk A, Molinaro M, Dwyre DM, Lane S, Matthews D, Wachsmann-Hogiu S

Structure-activity relationship among purpurinimides and bacteriopurpurinimides: trifluoromethyl substituent enhanced the photosensitizing efficacy.

Journal of medicinal chemistry

Gryshuk A, Chen Y, Goswami LN, Pandey S, Missert JR, Ohulchanskyy T, Potter W, Prasad PN, Oseroff A, Pandey RK

Nature: a rich source for developing multifunctional agents. Tumor-imaging and photodynamic therapy.

Lasers in surgery and medicine

Pandey RK, Goswami LN, Chen Y, Gryshuk A, Missert JR, Oseroff A, Dougherty TJ

In vivo stability and photodynamic efficacy of fluorinated bacteriopurpurinimides derived from bacteriochlorophyll-a.

Journal of medicinal chemistry

Gryshuk AL, Chen Y, Potter W, Ohulchansky T, Oseroff A, Pandey RK

Multimodality agents for tumor imaging (PET, fluorescence) and photodynamic therapy. A possible "see and treat" approach.

Journal of medicinal chemistry

Pandey SK, Gryshuk AL, Sajjad M, Zheng X, Chen Y, Abouzeid MM, Morgan J, Charamisinau I, Nabi HA, Oseroff A, Pandey RK

A novel approach to a bifunctional photosensitizer for tumor imaging and phototherapy.

Bioconjugate chemistry

Chen Y, Gryshuk A, Achilefu S, Ohulchansky T, Potter W, Zhong T, Morgan J, Chance B, Prasad PN, Henderson BW, Oseroff A, Pandey RK

Methyl pyropheophorbide-a analogues: potential fluorescent probes for the peripheral-type benzodiazepine receptor. Effect of central metal in photosensitizing efficacy.

Journal of medicinal chemistry

Chen Y, Zheng X, Dobhal MP, Gryshuk A, Morgan J, Dougherty TJ, Oseroff A, Pandey RK

Synthesis and photosensitizing efficacy of isomerically pure bacteriopurpurinimides.

Journal of medicinal chemistry

Chen Y, Sumlin A, Morgan J, Gryshuk A, Oseroff A, Henderson BW, Dougherty TJ, Pandey RK

Structural modifications of plumieride isolated from Plumeria bicolor and the effect of these modifications on in vitro anticancer activity.

The Journal of organic chemistry

Dobhal MP, Li G, Gryshuk A, Graham A, Bhatanager AK, Khaja SD, Joshi YC, Sharma MC, Oseroff A, Pandey RK

Functionalization of OEP-based benzochlorins to develop carbohydrate-conjugated photosensitizers. Attempt to target beta-galactoside-recognized proteins.

The Journal of organic chemistry

Li G, Pandey SK, Graham A, Dobhal MP, Mehta R, Chen Y, Gryshuk A, Rittenhouse-Olson K, Oseroff A, Pandey RK

A first comparative study of purpurinimide-based fluorinated vs. nonfluorinated photosensitizers for photodynamic therapy.

Photochemistry and photobiology

Gryshuk AL, Graham A, Pandey SK, Potter WR, Missert JR, Oseroff A, Dougherty TJ, Pandey RK