Exai Bio today announced new data demonstrating that its novel RNA-based and AI-driven liquid biopsy platform can detect breast cancer at the earliest stages and the smallest tumor sizes, including ductal carcinoma in situ (DCIS), using a standard blood sample. In a new early detection study building upon prior data, stage I breast cancer sensitivity was 87%, and tumor size T1a-b (10 mm or smaller) sensitivity was 81%, both at 90% specificity. Overall sensitivity across all invasive breast cancer stages was 88% at 90% specificity, far exceeding any DNA-based liquid biopsy performance. Exai additionally reported a sensitivity of 78% for DCIS at 90% specificity. These results will be presented at a poster session today at the San Antonio Breast Cancer Symposium (SABCS) 2023 meeting.
