This week, Nevan Krogan’s group posted a preprint describing a PPI network involving 100 ASD risk genes. The study, titled “A Foundational Autism Protein Interaction Atlas Reveals Molecular Convergence”, is posted on bioRxiv. The work provides insights into the molecular mechanisms of a subset of individuals with ASD who carry specific genetic mutations, and this map—the first map of its kind ever created for any neuropsychiatric disorder—provides a window into the development of novel therapeutics for those living with the condition.
