2025

• Steven Altschuler, PhD, Lani Wu, PhD, and Cathy Lomen-Hoerth, MD, PhD - Beyond Genetics: A Digital Health Platform for ALS and other Complex Diseases
• Mandar Aras, MD, PhD, Arun Padmanabhan, MD, PhD, and Yaser Abu-Mostafa, PhD - Automated Analysis of Echocardiographic Variables in Heart Disease
• Maryam Bijanzadeh, PhD, Reza Abbasi Asl, PhD, Adam Gazzaley, MD, PhD, and Andrew Krystal, MD - Towards Objective Depression Screening: Developing a Multimodal Brain Body Wearable Biomarker System
• Frank Brodie, MD, MBA and Daniel Schwartz, MD - Vitreoretinal Adhesion Therapy to Prevent Retinal Detachment
• Mauro Caffarelli, MD and Edilberto Amorim, MD - NeuroSentry: EEG Software for Non-Expert In-Hospital and Periprocedural Stroke Detection
• Ritchie Chen, PhD, MSc - Targeted Gene Delivery in the Brain Using Bio-derived Lipid Nanoparticles to Treat Intractable Epilepsies
• Roshanak Irannejad, PhD, Kevan Shokat, PhD, and Jeffrey Olgin, MD - Novel Approach to Inhibit Beta-Adrenergic Signaling in Diastolic Heart Dysfunction Using a Spatially Restricted Beta-Blocker
• Tyson Kim, MD, PhD - Multiphoton Aqueous Flowmetry and Multimodal Glaucoma Therapy
• Bin Liu, PhD, and Tom Arnold, MD - Tissue-specific Choline Transporter Antibody for GBM and AML Therapy
• Susan Lynch, PhD - Preclinical Development of Protoporphyrin-Producing Escherichia Coli as a Prophylaxis for Anaphylaxis
• Kristen Mengwasser, MD, PhD, and Alexander Marson, MD, PhD - B-Scan: Mapping B-Cell Receptor and Antibody Specificity using a Mammalian Genome-wide Screening Platform
• Julian Motzkin, MD, PhD, and Prasad Shirvalkar, MD, PhD - Intracranial Neural Biomarkers for Chronic Primary Pain Diagnosis and Treatment Selection
• Feroz Papa, MD, PhD and Bradley Backes, PhD - Kinase Inhibitors of the Unfolded Protein Response Sensor/effector IRE1alpha to Treat Type 1 Diabetes
• Neel Pasricha, MD, and Onur Cil, MD, PhD - Repurposed Macropinocytosis Inhibitor Eye Drop for Antibody-Drug Conjugate (ADC) Corneal Toxicity
• Pedro Pinheiro-Chagas, PhD, Bruce Miller, MD, Katherine Possin, PhD, Maria Luisa Gorno-Tempini, MD, PhD, Bill Seeley, MD, and Andreas Rauschecker, MD, PhD - Memory and Aging Center Co-pilot: A Multi-Agent AI System for Neurodegenerative Disease Diagnosis
• Danielle Swaney, PhD, and Einar Krogsaeter, PhD - Correcting Subcellular Protein Trafficking to Treat Alzheimer’s Disease
• Raymond Swanson, MD - Blocking Cytotoxicity of α-Synuclein Aggregates for the Treatment of Parkinson’s Disease
• Jet Vonk, PhD and Maria Luisa Gorno-Tempini, MD, PhD - A Speech-Based Algorithm for Differential Diagnosis and Longitudinal Monitoring of Dementia
• John Yue, MD, Mahmoud Elguindy, MD, PhD, and Geoffrey Manley, MD, PhD - Evaluation of Blood-Based Proteomic and RNA Biomarkers to Improve Traumatic Brain Injury Diagnosis and Prognostication

 

2024

• Aaron Kornblith, MD - AI-enabled Point-of-care Ultrasound Solution and Clinical Integration in the Emergency Department
• Adam Abate, PhD and Charles Chiu, MD, PhD - Hundred-plex Digital PCR with PACE to Advance Neurologic Infection Diagnostics
• Andreas Rauschecker, MD, PhD - Finding Our Neuroimaging Twins and Imaging Neighbors (FOUNTAIN): A Brain MRI Similarity Search Engine
• Doris Wang, MD, PhD, Hamid Fekri Azgomi, PhD, and Rithvik Ramesh - Development of Personalized Adaptive Deep Brain Stimulation for Enhancing Gait Functions in Patients with Parkinson’s Disease
• Charles Craik, PhD - A Structure-Guided Approach to Antibody-Based Herpesvirus Inhibition
• Jacob Young, MD, John De Groot, MD, and Mitchel Berger, MD  - Development of Hand-held Intraoperative Focused Ultrasound Device for Glioma Patients
• Joseph Sabatino, MD, PhD and Yu Zhou, PhD - Novel Bispecific Antibody to Disrupt the B Cell-T Cell Axis in Multiple Sclerosis and Other Autoimmune Diseases
• Juan Qin, PhD - Harnessing Immune Checkpoint Inhibitors for Cardiac Repair
• Kyle Cromer, PhD - Enhancing Erythropoiesis Using Base Editors
• Linda Giudice, MD, PhD and Susan Fisher, PhD - Biomarker Discovery to Diagnose Endometriosis: A Pilot Study
• Luis Savastano, MD, PhD and Can Senol, MD - A Minimally Invasive System for Brain Surgery
• Nadav Ahituv, PhD - Engineered Adipocytes that Outcompete Tumors for Reagents as a Novel Cancer Therapy
• O'Rese Knight, MD - Mercury: A Wearable Intraocular Pressure Monitor
• Tommaso Di Ianni, PhD - Minimally Invasive Closed-loop Neuromodulation via Combined Focused Ultrasound and Functional Ultrasound Imaging
• William Krause, PhD, Muriel Babey, MD, and Holly Ingrahm, PhD  - Optimizing a Novel Osteoanabolic Hormone to Treat Fragile Bone Diseases

 

2023

• Reza Abbasi-Asl, PhD and Simon Little, PhD - Interpretable Machine Learning for Video-Assisted Diagnosis and Tracking of Parkinson’s Disease
• Matthew Amans, MD - A Device for Diagnosis of Pulsatile Tinnitus
• Jeannie Bailey, PhD and Ryan Halvorson, MD - A Mobile Application for Digitally Tracking and forecasting Patient-Centric Response to Musculoskeletal Treatment
• Mauro Caffarelli, MD and Edilberto Amorim, MD - Electrofunctional Imaging for Real-Time Detection of Large Vessel Ischemic Stroke Using Electroencephalography
• Claire Clelland, MD, PhD - CRISPR Gene Therapy for Neurodegenerative Disease: Target Gene Correction for ALS
• Steve Francis, PhD, MS - An Extracellular Vesicle Based Approach for Identifying High Risk Pancreatic Cyst Lesions
• Maria Garcia, MD, MAS, MPH, Lisa Ochoa-Frongia, MD, Valy Fontil, MD, MAS, and Mark Pletcher, MD, MPH - Optimizing Depression Care Delivery in Primary Care Through a Technology-Enhanced Intervention (Optimize-D-Rx)
• Ezequiel Goldschmidt, MD, PhD, Ronald Fearing, PhD, SB, SM, and Ishan Kanungo - Soft Locomotive Robot Driven by Multiple Independent Pouch Motors to Perform Minimally Invasive Paranasal Sinus Biopsies
• Brian Haas, MD - NeedleGPS: the Guided Positioning System for Needle Insertions
• Alexander Haddad, MD, Manish Aghi, MD, PhD, MAS, and Noriyuki Kasahara, MD, PhD - A Synthetic Replicating Retroviral Platform for Glioblastoma Viral Immunotherapy
• Lohith Kini, MD, PhD, Ankit Khambhati, PhD, and Peter Hadar, MD, MSTR - AIMSS: the AI-Based Mobile Stroke Scale
• Alexander Lin, MD, MBA, FACS - Improving Health Equity of Children with Cleft Palate - Artificial Intelligence to Improve Early Detection of Surgical Speech Problems
• Dengke Ma, PhD and Dean Sheppard, MD - Targeting TMEM-131 as a Novel Approach to Treating Pulmonary Fibrosis
• Minnie Sarwal, MD, PhD and Swas Sur, PhD - Novel Renoprotective Drug Target Discovery in an Established Renal Tubular Injury Model
• Arun Wiita, MD, PhD - Non-Myeloablative OR-Gated Car-T Cell Therapy for Acute Myeloid Leukemia

 

2022

• Nadav Ahituv, PhD and Ofer Yizhar-Barnea, PhD Neomer Diagnostics: Next Generation Liquid Biopsy for Early Cancer Detection
• Lauren Asarnow, PhD Improving Sleep Among Adolescents through Digital Health Solutions
• Andy Chang, PhD and Alexandra Scharr, PhD Targeting a Non-opioid Signaling Pathway to Reverse Opioid-induced Respiratory Depression
• Emily Finlayson, MD, MPH, MS PrehabPal: AI-powered Surgery Preparation for Vulnerable Older Adults
• Alexander Haddad, MD, Manish Aghi, MD, PhD, MAS, and Noriyuki Kasahara, MD, PhD Synthetic Novel Replicating Retroviral Gene Therapy Platform for the Treatment of Glioblastoma
• Keith Hansen, MD, James Gardner, MD, PhD, and Garett Roll, MD, FACS DIATIRO Kidney Cooling Jacket: A Regelation Device to Address the Organ Shortage and Improve Transplant Longevity
• Matthew Jacobson, PhD N-(4-(dimethylamino)but-2-enyl)-7-chloro-quinolin-4-amine (DAQ) for Treating Chloroquine-resistant Malaria
• Noriyuki Kasahara, MD, PhD Universal Stem Cell-based Delivery of Tumor-Selective Retroviral Replicating Vectors
• Anastasia Keller, PhD and Jeannie Bailey, PhD Application of Transcutaneous Spinal Cord Stimulation for Treatment of Chronic Low Back Pain
• Aras Mattis, MD, PhD Therapeutic Targeting of TM6SF2 Fatty Liver Disease
• S. John Liu, MD, PhD, Luke Gilbert, PhD, David Raleigh MD, PhD, and William A. Weiss, MD, PhD High-resolution Discovery of Novel Therapeutics for Glioblastoma Using in vivo CRISPR Perturb-seq
• Timothy McCalmont, MD, Michael Wang, MD, Avideh Zakhor, PhD and Neil Neumann, MD, PhD Quantifying Invasive Tumor Volume by Deep Learning to Improve Malignant Melanoma Prognosis
• Julie Saba, MD, PhD Adeno-associated Virus-mediated SGPL1 Gene Therapy
• Julie Schallhorn, MD, MS and Nailyn Rasool, MD Transcutaneous Electrical Stimulation for Sustained Eyelid Closure
• Jeffrey Sharon, MD Development and Validation of a Machine Learning Based Smartphone Application for Point of Care Vestibular Testing

 

2021

• Nirav Bhakta, MD, PhD, Xavier Orain, and Franklin Heng Breathily: Computer Vision-based Spirometry
• Miles Conrad, MD, MPH, Phillip Messersmith, PhD, and Mark Wilson, MD A Novel Hydrodissection Material for Percutaneous Tumor Ablation
• Nicole Jiam, MD and David Conrad, MD The PolyBarb Nasal Implant System: A Novel Steroid-eluting Absorbable Drug Delivery Platform for Inflammatory Diseases of the Nose
• Chaz Langelier, MD, PhD A Rapid Host Gene Expression Classifier to Enhance COVID-19 Diagnosis and Predict Outcomes
• Bin Liu, PhD Therapeutic Development of a Novel Wnt Agonist Antibody that is Not a Ligand Surrogate
• David Raleigh, MD, PhD, Jeremy Reiter, PhD, and William Chen, MD A Gene Expression Panel Biomarker for Meningioma Risk-Stratification
• Julie Saba, MD, PhD Adeno-Associated Viral Mediated SGPL1 Gene Replacement for Sphingosine Phosphate Lyase Insufficiency Syndrome (SPLIS)
• Prasad Shirvalkar, MD, PhD and Lawrence Poree, MD, PhD EEG Guided Personalized Spinal Cord Stimulation for Chronic Pain
• Ida Sim, MD, PhD Patient-Generated Data (PGD) Cloud: A Public Digital Utility for Patient-Generated Data as a Service
• Yao Sun, MD, PhD  NeoTune: A Tuneable Non-invasive High-Frequency Ventilation Device
• Aaron Tward, MD, PhD and Vicente Planells-Palop, PhD Next-Generation Human Squamous Cell Cancer Modeling for Drug Discovery
• Erik Ullian, PhD Investigating Neuronal Cell Autonomous and Non-Cell Autonomous Mechanisms of Degeneration
• Lei Wang, PhD Developing Irreversible Covalent Protein Drugs for Treating SARS-CoV-2 Infection via PERx

 

2020

• Diane Barber, PhD Screening Methodology and Therapeutic Discovery Targeting Dysregulated Lysosomes in Cancer and Neurodegenerative Disorders
• John Burke, MD, Prasad Shirvalkar, MD, PhD and Doris Wang, MD, PhD Discovering the Biomarkers of Lower Limb Movement and Locomotion Through Human Spinal Cord Recording
• Jennifer Chen, MD, Bill DeGrado, PhD, and John Gordan, MD, PhD Targeting the Ceramide Pathway for the Treatment of NASH and Hepatocellular Carcinoma
• Pamela England, PhD and Matt Jacobson, PhD Small Molecule Therapeutics Targeting Nurr1 for the Treatment of Parkinson’s Disease
• Valy Fontil, MD, MAS, MPH Engage-Rx: Harnessing Cloud-Based Technology for Comprehensive Management of Hypertension through Patient Engagement and Clinical Decision Support
• Ying Han, MD, PhD A Gel-Based System for Long-Term Release of Ocular Medication
• Matt Jacobson, PhD Development of Small Molecule Drug for the Treatment of Chloroquine-Resistant Malaria
• Chaz Langelier, MD, PhD Integrated Host/Microbe Metagenomics (iHMM) for Precision Diagnosis of Sepsis
• Leqian Liu, PhD and Adam Abate, PhD Fast and Reproducible Synthesis of Multicellular Tumor Organoids
• John Metcalfe, MD, PhD, MPH Handheld DNA Sequencing for Rapid Detection of New and Repurposed Drug Resistance in M. tuberculosis
• Gopika Nair, PhD Identification of Novel Regulators of Human Pancreatic Beta Cell Mass Using Stem Cell-Based HTS Platform
• Nicole Paulk, PhD and Joseph DeRisi, PhD, and David Raleigh MD, PhD A Novel Platform Approach to Immunotherapy via Non-Oncolytic Viral Gene Therapy for Glioblastoma
• Shuvo Roy, PhD An Implantable Device for Fluid Removal for Heart Failure Patients
• James Rubenstein, MD, PhD Antibodies Targeting Novel Innate Immunity Mechanisms as Cancer Therapeutic
• Matthew Stachler, MD, PhD Risk Stratification Biomarkers of Patients with Low-Grade Dysplastic Barrett's Esophagus
• Doris Wang, MD, PhD Decoding the Neural Signatures of Gait in Parkinson's Disease

 

2019

• John Chorba, MD Targeting PCSK9 to Treat Atherosclerosis
• Peter Haggie, PhD, Onur Cil, MD, PhD, Alan Verkman, MD, PhD Inhibitors for Treatment of Kidney Stones and Constipation
• Jeff Neitz, PhD In Vivo Characterization of Advanced Small Molecule Inhibitors of a Target for Lung and Breast Cancers
• Tejal Desai, PhD, and Wendell Lim, PhD Novel Approach for Ex Vivo and In Vivo Expansion of Native and CAR-modified T Lymphocytes
• Ian Seiple, PhD, and Jim Wells, PhD Development of Antibody-PROTAC Conjugates for the Treatment of Cancer
• Sourav Bandyopadhyay, PhD Biomarkers for Molecularly-Targeted Therapies for Lung Cancer
• Michael Shlipak, MD, and Michelle Estrella, MD Point-of-Care Functional Monitoring in Hospitalized Heart Failure
• Vamsi Aribindi, MD, and Shuvo Roy, PhD Silicon Micropore-Based Parallel Plate Membrane Oxygenator for Long Term Lung Replacement
• Hanmin Lee, MD SmartDerm: A Closed-Loop Pressure Ulcer Prevention System
• Pamela Munster, MD Intercepting Early Stage Prostate Cancers
• Veeshal Patel, MD, MBA, and Mitchel Berger, MD Berger Brain Mapper: Development of a Handheld Tool for Cortical Stimulation
• Ling Zhan, DDS, PhD, and Wu Li, MD, PhD Novel Peptides for Dental Applications
• Edward Chang, MD, and Heather Dawes, PhD, Nimbostratus: Cloud-Based Clinical Data Platform for Neural Interface Technologies
• Aaron Kornblith, MD, Rima Arnaout, MD, and Rachael Callcut, MD Novel Advanced Machine Learning for Pediatric application
• Prasad Shirvalkar, MD, PhD, and Lawrence Poree, MD, PhD Biomarker Based Personalized Spinal Cord Stimulation for Chronic Pain
• Eric Chow, PhD, and David Patterson, PhD Next-Generation Drug Screening with Highly Multiplexed Single-Cell Sequencing
• Wallace Marshall, PhD Algae Based Platform for Protein Expression and Production

 

2018 - Spring

• Steven Altschuler, PhD The Development of Targeting Therapy to Enhance EGFR Targeting Drug Efficacy in NSLC
• Rima Arnaout, MD Cardiovascular Diagnostics Using Deep Machine Learning
• Bradley Backes, PhD and Feroz Papa, MD, PhD Proprietary IRE1alpha Inhibitors for Systemic Indications
• Robert Blelloch, MD, PhD Development of Small Molecule Inhibitors of Immune Checkpoint Protein Presentation
• Charles Craik, PhD and Kaitlin Hulce, PhD Candidate Protease Inhibition as an Alternative Treatment for Herpesvirus Infection
• Hani Goodarzi, PhD Developing the Next Generation of Liquid Biopsies
• Terumi Kohwi-Shigematsu, PhD and Yoshinori Kohwi, PhD Post Translationally Modified Genome Organizer as a Target for Cancer Diagnosis and Therapy
• Ian Metzler, MD and Thomas Chi, MD Ultrasound Visible Percutaneous Dilation System
• Aparna Sundaram, MD, Bill DeGrado, PhD, Dean Sheppard, MD and Hyunil Jo, PhD Integrin Inhibitors to Mitigate Smooth Muscle Contraction in Asthma
• Shant Vartanian, MD Percutaneous Fistula Device for Dialysis Access
• Rong Wang, PhD Development of an Inhibitory Antibody as a Molecular Therapy for Brain Arteriovenous Malformation

 

2017 - Spring

• Nadav Ahituv, PhD and Navneet Matharu, PhD CRISPRa Therapeutics for Autosomal Dominant Polycystic Kidney Disease
• Chris Diederich, PhD and Matthew Adams Deployable Ultrasound Energy Systems for Endoluminal and Laparoscopic Therapeutic Interventions
• Karin Gaensler, MD Trileukevax: a Next Generation Autologous Immunotherapy for Leukemia
• Jason Gestwicki, PhD Inhibitors of the cis-trans peptidyl-prolyl isomerase, Pin1
• Jennifer Grandis, MD and Daniel Johnson, PhD Development of a Cyclic STAT3 Decoy Oligonucleotide for Cancer Therapy
• Akiko Hata, PhD and Giorgio Lagna, PhD Novel Drug Screening Strategy for Fragile X Syndrome
• Jeremy Keenan, MD, MPH and Kristen Aiemjoy, MCR/MPH/MS A New Low-cost Test for Detecting Soil-transmitted Helminth Infections in Young Children
• Terumi Kohwi-Shigematsu, PhD and Yoshinori Kohwi, PhD Cancer Diagnostic Tools for Identifying Metastasis-competent Tumor Cells within Tumors
• Pamela Munster, MD MayaLife - Developing Silastic Tubing for Local Delivery of Hormonal Therapy – a Novel Approach to Breast Cancer Treatment and Prevention
• Snehlata Oberoi, BDS, DDS, MDSD and Philip Chung Innov8 Retainer: Improving Orthodontic Retention with Digital Health
• Minnie Sarwal, MD, PhD TRAP: A Novel Organ Transplant Monitoring Tool
• Gilmer Valdes, PhD and Timothy Solberg, PhD Mediforests: Critical Independent Validation of Decision Support Systems in Medicine
• Maria Wei, MD, PhD Real-time Precision Melanoma Screening Using Deep Neural Networks

 

2017 - Fall

• David Conrad, MD and Romain Roux, MS Tracheostamy Alarm and Monitoring System
• Jesse Courtier, MD, Lan Vu, MD and Ben Laguna, MD RadHA, A Novel Augmented Reality Application for Improved Pre-Surgical Planning Using 3D Holographic Radiology Images
• Stefan Habelitz, PhD Polymer Induced Liquid Precursor Treatment for the Repair of Dental Caries
• Hobart Harris, MD, MPH Prevention of Incisional Hernias
• Harini Sarathy, MD and Dr. Shuvo Roy, PhD Blood Flow Effects on Silicon Substrates
• Elliot Stieglitz, MD Implementation of DNA Methylation Based Test to Predict Outcome in Juvenile Myelomonocytic Leukemia

 

2016 - Spring

• Ying Han, PhD, MD A Novel Drainage Device to Reduce Fibrosis in Glaucoma Surgery
• Caroline Jordan, PhD Micro Resonant Marker: A Novel Device for Catheter Visualization during Interventional MRI
• Sunghoon Kim, MD A Novel Shunt for the Treatment of Hydrocephalus
• Paul Marinec, PhD Enhancing the Delivery of Therapeutic Antibodies into RAS-Driven Tumor Cells
• Holly Martin, MD Mobile Health Solution for Improved Neonatal Resuscitation: BREATH
• Jyoti Mishra, PhD NeuroACE - a novel mobile mental health app for real-world neural and cognitive diagnostics
• Corey Raffel, PhD, MD A Targeted Oncolytic Measles Virus for the Treatment of Many Tumor Types
• Pierre Theodore, MD Otto: Digital Rehabilitation Device for Post-Stroke Motor Recovery
• Adam Renslo, PhD Optimization and Biological Characterization of Novel Carbapenemase Inhibitors
• Stanley Rogers, MD Esophageal Manometry for Airway Protection (EMAP): Medical device solution to decrease risk of aspiration and respiratory compromise in surgical candidates
• Brian Shoichet, PhD A µ-opioid analgesic without respiratory depression & addictive liabilities
• Ma Somsouk, MCR/MPH/MS, MD Transforming Technical Training through Individual Trainee Record and Competency Solution (iTRACS)

 

2016 - Fall

• Dena Dubal, MD, PhD Brain Resilience: A New Approach to Treating Neurodegenerative Disease
• Richard Fidler, RN, PhD, CRNA & Xiao Hu, PhD Develop SuperAlarm Front-End Clinical User Interface
• Emily Finlayson, MD PrehabPal: Refining and Testing Digital Support for Frail Elderly Preparing for Surgery
• Kim Kirkwood, MD & Charles, Craik, PhD Development of Fluorogenic Substrates for the Diagnosis of Pancreatic Cysts
• Chaz Langelier, MD, PhD & Emily Crawford, PhD Precision Detection of Antimicrobial Resistant Respiratory Pathogens via Next Generation Sequencing
• Hanmin Lee, MD SmartDerm Algorithm for Ulcer Risk Assessment (AURA): A Pressure Ulcer Risk Stratification Tool
• Shuvo Roy, PhD An Intervascular Ultrafiltration-based Bioartificial Pancreas
• Minnie Sarwal, MD, PhD Predicting Antibody Mediated Rejection by the Precision Panel Reactive Antibody (PPRA) Assay
• Ian Seiple, PhD A Platform for the Synthesis of Antibiotics that Target Bacterial Ribosomes
• Elliott Sherr, MD, PhD & Dylan Chan, MD, PhD A Novel Approach to the Treatment of Hearing Loss
• Jeoung-Sook Shin, PhD Identification of a Small Molecule Inhibitor for Treatment of Asthma
• Elaine Tseng, MD & Liang Ge, PhD Development of a Removable and Replaceable Transcatheter Aortic Valve
• Josh Woolley, MD, PhD Validation of the Computerized Assessment of Mental Status (CAMS): A Multi-modal Tool for the Objective Assessment of Social-emotional Behavior and Psychological Health
• Esther Yuh, MD, PhD Machine Learning for Rapid Head CT Analysis in Neurological Emergencies

 

2015 - Spring

• Cassandra Calloway, PhD Non-Invasive Prenatal Testing for Beta Hemoglobinopathies
• Albert Chang, MD, PhD 89Zr-Radiolabeled ImmunoPET as a Non-Invasive Imaging Biomarker to Predict Response to Cancer Immunotherapy
• John Chorba, MD Discovery of Small Molecule Inhibitors of PCSK9
• Emily Finlayson, MD Prehab Pal: Preparing the Elderly for Surgery
• Linda Franck, RN, PhD, FRCPCH, FAAN We3 Health: Improving Preterm Infant Outcomes with Family Integrated Care and Mobile Devices
• Danica Fujimori, PhD Inhibition of Oncogenic Demethylases: Potential Therapeutic Targets in mCRPC
• Jason Gestwicki, PhD Novel Antibiotic Target for Multi-Drug Resistant Bacterial Infections
• Xiao Hu, PhD Superalarm: An Advanced Analytics Platform for Precise Patient Monitoring
• Hanmin Lee, MD SmartDerm: A Monitoring System for Decubitus Ulcer Prevention – Phase II
• Tippi MacKenzie, MD In Utero Hematopoietic Cell Transplantation for Alpha Thalassemia Major
• Adam Renslo, PhD Antibody Drug Conjugates Based on Novel Linkers
• Minnie Sarwal, MD, PhD Customized Panel Reactive Antibody Assay for Transplant Care
• Insoo Suh, MD Lamprey Retractor

 

2015 - Fall

• Kamran Atabai, MD Commercializing the use of recombinant milk fat protein to increase the absorption of nutrients in malabsorption syndromes
• Chelsea Bahney, PhD OsteoNova: a cartilage based alternative to bone grafting
• Linda Franck, RN, PhD, FRCPCH, FAAN We3 Health: Improving Preterm Infant Outcomes with Family Integrated Care and Mobile Devices
• Anthony Kim, MCR/MPH/MS, MD MissionControl-Stroke: Shared E-Checklist and Communications Platform for Time-Sensitive Code Stroke Response
• Liviu Klein, MD, MS Novel, low-power, non-invasive pressure sensor for heart failure monitoring
• Marc Levin, MD, PhD Small Molecule CFTR Activators for Dry Eye Therapy
• Elyssa Margolis, PhD Developing delta opioid receptor agonists for the treatment of alcoholism
• Hideho Okada, MD, PhD Novel Mutation-derived Neoantigen for T Cell Therapy in Gliomas
• Donald McCarthy, PhD Commercialzing the use of recombinant Mfge8 to increase the absorption of nutrients in malabsorption syndromes
• Rada Savic, PharmD, PhD Ensemble modeling & simulation for precision dosing of biologics
• John Shepherd, PhD The Selfie as a monitor of healthy body composition
• Michael Shlipak, MD, MPH The Intelligent Dipstick
• Danielle Schlosser, PhD Evaluating the feasibility of scaling PRIME-d, a novel mobile platform to treat individuals with depression in the healthcare system
• Insoo Suh, MD Lamprey Surgical Instrument
• Alan Verkman, MD, PhD Small-molecule CFTR Activators for Treatment of Constipation

 

2014 - Spring

• Scott Baraban, PhD Zebrafish as a Model for Drug Discovery in Epilepsy
• Charles Chiu, MD, PhD Clinical Validation of a Multiplexed Diagnostic Assay for Lyme Disease and Other Tickborne Illnesses During Acute Infection
• Ellyn Cohen, PhD Development of a Mobile Application for Increasing Access to UCSF Clinical Trials
• Pamela England, PhD Small Molecules Targeting Parkinson’s Disease
• Michael Evans, PhD Synthesis and Evaluation of Radioligands targeting the glucocorticoid receptor in Enzalutamide resistant prostate cancer
• Michael Harrison, MD MagnaGrasp: Proof of Concept Validation of a Detachable, Adjustable, Magnetically Anchored Grasper for Minimally Invasive Surgery
• Xiao Hu, PhD Prospective Validation of SuperAlarm Technology and Development of the Infrastructure necessary to support a Clinical Trial
• Ron Keizer, PhD Cloud-Based Dose-Individualization of Busulfan in Children
• Marc Levin, MD, PhD Small Molecule Therapy for Dry Eye Therapy
• Michael Matthay, MD Mesenchymal Stem Cell Derived Biologics for Treatment of Acute Respiratory Distress Syndrome
• Catherine Park, MD A Real-Time Intraoperative Fluorescent Imager for Microscopic Residual Tumor
• Lei Stanley Qi A Novel Epigenetic Therapeutic Strategy For Treating Beta-Thalassemia
• Jeroen Roose, PhD Development of a Diagnostic Biomarker for Colorectal Cancer
• Rebecca Sudore, MD A Novel Website to Preparing Diverse Older Adults for Medical Decision Making
• Laura van't Veer, PhD Functional Detection of the Targetable Oncogenic Kinome in Cancer
• Lin Ye, PhD Development of Functional Cure of HIV-1 Infection Using Gene Modification in Patient’s Own Hematopoietic Stem Progenitor Cells

 

2014 - Fall

• Anupama Arun, PhD SmartBrace: Remote Monitoring of Patient Compliance and Treatment Efficacy for Medical Devices
• Tejal Desai, PhD Nano-Engineered, Non-Thrombotic Vascular Grafts
• Robert Flavell, MD, PhD Agents for Positron Emission Tomography Sensing of Acidic Tumoral Microenvironment
• Hobart Harris, MD Prevention of Incisional Hernias
• Allison Kaup, PhD NeuroBloom: Development of User Testing of a 'Mobile Senior Center' App to Promote Cognitive Health and Overall Well-being in Older Adulthood
• Bin Liu, PhD Development of an Antibody Drug Conjugate into a Potent and Selective Anti-cancer Therapeutic
• Ngoc Ly, MD, MPH Spiritus Mobile: A Portable Device to Monitor and Track Lung Function and Promote Asthma Self-Management
• Stephen Nishimura, MD Targeting of Integrin-Mediated TGF-β Activation for Fibroinflammatory Disorders with Engineered Monoclonal Antibodies
• Jean Pouliot, PhD and Josephine Chen, PhD AUTOmated Deformable Image Registration Evaluation of Confidence Tool (AUTODIRECT)
• Shuvo Roy, PhD High-Efficiency External Ambulatory Lung (HEAL)
• Elliott Sherr, MD, PhD Development of a Blood-Based Biomarker for Autism
• Laura van ‘t Veer, PhD, Jean-Philippe Coppe, PhD Functional Detection of the Targetable Oncogenic Kinome of Cancer
• Benjamin Yeh, MD Biphasic Enteric CT Contrast Agents
• David Young, MD Detecting Pressure Ulcers Using Non-Invasive Impedance Mapping
• Ling Zhan, DDS, PhD Salivary Screening to Identify High-Caries-Risk Children
• Corinna Zygourakis, MD TrueDoc: Development of a Doctor-Focused Mobile App that Decreases Medical Costs

 

2013 - Spring

• Mark Anderson, MD, PhD Generation of a functional thymus from stem cells for the induction and maintenance of immune tolerance
• Conor Caffrey, PhD Lead optimization of a novel small molecule therapy for the neglected tropical disease, schistosomiasis
• William DeGrado, PhD & Ethan Weiss MD GPR81 agonists conjugated to JAK2 antagonists as therapeutics for treatment of type II diabetes
• Tejal Desai, PhD TiO2 nanotubular coatings to prevent cardiac fibrosis at electrode/myocardial interface of CRM devices
• Yoshimi Fukuoka, PhD, RN An innovative weight loss program for spanish-speaking latinos at high risk for Type 2 Diabetes
• Pierre Gourraud, PhD, MPH Development of MS Bioscreen at UCSF Clinics
• Daphne Haas-Kogan, MD Determinants of response and resistance in pediatric low-grade glioma
• Alexander Johnson, PhD & Clarissa Nobile PhD Development of Therapeutics to Treat Persistent C.albicans Biofilm Infection
• Kimberly Kirkwood, MD Early Diagnosis of Pancreatic Cancer Using a Non-Invasive Imaging Tool
• Susana Ortiz-Urda, MD, PhD Functionalized nanostructures for detection and treatment of uveal melanoma
• Travis Porco PhD, MPH Computer vision assessment of trachoma photographs
• Katherine Possin, PhD The UCSF Tab-CAT: a novel tablet-based cognitive assessment tool for dementia
• Danielle Schlosser ,PhD Encouraging Health Promoting Behaviors Using a Novel Personalized Real-time Motivational Enhancement Mobile Application
• Marshall Stoller, MD & Herman Bagga, MD Bladder Volume Sensing Device
• Thea Tlsty, PhD Endogenous Pluripotent Somatic Cells from Adult Human Tissue with Potential for Regenerative Medicine: Applications in Corneal Transplantation
• Leor Weinberger, PhD Development of a Novel Platform to Identify Small-Molecule Inhibitors of CMV Infection
• Benjamin Yeh, MD Novel CT Enteric Contrast Agents
• Ling Zhan DDS, PhD Screening of Genes in Mutans Streptococci related to Bacterial Transmission and Caries Risk in children

 

2013 - Fall

• Adam Abate, PhD PACS: PCR-activated cell sorting
• Aditi Bhargava, PhD Delivery Challenges in Developing New Treatments for Inflammatory Bowel Disease (IBD)
• Jason Gestwicki, PhD Non-Surgical Treatment for Cataract
• Roeland Hancock, PhD Early Mobile Screening for Reading Disorder Risk
• John Kane, PhD Development of a Blood test for Imminent Acute Cardiac and Cerebrovascular Events
• Ron Keizer, PhD Cloud-Based Dose-Individualization of Busulfan in Children
• Hanmin Lee, MD SmartDerm: A Monitoring System for Decubitus Ulcer Prevention
• Holly Martin, MD BREATH: Baby Resuscitation Enhanced - A Tech Helper
• Sima Suhas Pendharkar, MD, MPH Health Passport: A Passport to Wellness (A Digital Patient/Physician Communications Tool)
• Travis Porco, PhD Computer vision assessment of trachoma photographs
• Jean Pouliot, PhD AUTOmated Deformable Image Registration Evaluation of Confidence Tool (AUTODIRECT)

 

2012 - Spring

• Aaron Neinstein, MD, and Jenise Wong, MD, PhD Diabetes 3.0
• Conor Caffrey, PhD Developing a new chemotherapeutic for treatment of the neglected tropical disease, schistosomiasis
• John Chorba, MD Targeting the serine protease PCSK9 via covalent complementarity
• Charles Craik, PhD Validation of KSHV protease as a therapeutic target through allosteric inhibition
• Tejal Desai, PhD Nanoengineered thin film devices for ocular drug delivery
• John Fahy, MD Modified carbohydrate derivatives as novel reducing agents for the treatment of pathologic mucus in acute and chronic airway disease.
• Ari Green, MD Retinal imaging of amyloid-beta as a screening tool for glaucoma and Alzheimer's disease.
• Wolfgang Korn, MD Development of a predictive marker for sensitivity to treatment with MEK and EGFR
• Peder Larson, PhD Simultaneous Perfusion and metabolic imaging in a prostate cancer
• Robin Shaw MD, PhD A novel biomarker for heart failure based on cardiomyocyte biology
• Jay Stewart, MD A novel photodynamic therapy for the treatment of infectious keratitis
• Ashley Ward, MD Targeting hyperactive Ras with kinase inhibitors in juvenile myelomonocytic

 

2012 - Fall

• Adam Abate, PhD Detection and molecular profiling of cancer cells with Megadroplet Arrays
• Nancy Boudreau, PhD Topical HoxA5 gene therapy for Squamous Cell Carcinoma
• Jonah Chan, PhD A Binary Indicant of Myelination using Micropillar Arrays: A high-throughput screening platform for identifying remyelination therapeutics for Multiple Sclerosis
• Michael Conte, MD Pro-Resolving Vascular Devices
• Brian Feeley, MD Affordable 3-Dimensional Motion Analysis to Evaluate Lower Extremity Injury Risk
• John Gross, PhD Inhibition of HIV infectivity by targeting the Ubiquitin Proteasome System
• Michael Harrison, MD Amnioseal: Preventing premature birth in fetal intervention
• Roberta Keller, MD Antenatal sildenafil to prevent neonatal pulmonary hypertension in severe fetal diaphragmatic hernia
• Ngoc Ly MPH, MD Promoting Asthma Self-Management through an Interactive AsthmaMD Mobile App
• Mary Nakamura, MD A Recombinant Fusion Protein that redirects VEGF to actively kill cancer cells: R1FasL
• Yong Pang, PhD Quantitative Assessment of Liver Fat using Fast MR Imaging and 8-Channel Microstrip Coil Array
• Catherine Park, MD Development of a Real-Time Intraoperative Fluorescent Imager for Microscopic Residual Tumor
• Anand Patel, MD Intravenous Chemotherapy Filter: A Novel Device for High Dose Chemotherapy Delivery During Transarterial Chemoembolization
• Jayant Rajan, MD Estimation of the prevalence of chronic disease in an urban slum population in Brazil using a mobile computing platform
• Shuvo Roy, PhD Enabling the Feasibility Demonstration of a Bioartificial Pancreas
• Marshall Stoller, MD, Herman Bagga, MD, and Aenor Sawyer, MD A Novel Device to Promote Ambulation of the Hospitalized Patient
• Naomi Stotland, MD Pregnancy Weight Gain Coach—A Smartphone App
• Leslee Subak, MD Novel mHealth app and embedded platforms (wearable devices) for urinary incontinence treatment and research
• Francis Szoka, PhD Oral and Pulmonary Delivery of Proteins
• Lili Zhou, PhD Novel strategies to predict and enhance the activity of natural killer cells against Multiple Myeloma

 

2011 - Spring

• Adam Gazzaley, MD, PhD Development of integrated physical and cognitive therapeutic software
• Lily Jan, PhD Novel blockers of TMEM16A-CaCC calcium-activated chloride channels for asthma treatment
• Jay Nadel, MD Use of EGFR inhibitors in the treatment of respiratory viral infections including virus-induced asthma exacerbations
• Douglas Nixon, MD, PhD A monoclonal antibody to cure HIV-1 infection
• Michael Page, PhD In vivo diagnostics for cardiovascular disease
• Paul Simpson, MD Treatment of cardiomyopathy and heart failure
• Louise Swainson, PhD The use of synthetic peptidoglycan-peptide conjugates for the induction of antigen-specific tolerance in autoimmune disease

 

2011 - Fall

• Adam Abate, PhD Robust detection and genotyping of rare circulating tumor cells in human blood
• Christopher Barnett, MD, MPH Evaluation of the acute hemodynamic effects of dark chocolate in patients with WHO Group I pulmonary arterial hypertension
• Aditi Bhargava, PhD Targeted delivery of RNAi molecules for treatment of neuronal pathophysiologies
• Hobart Harris, MD Prevention of incisional hernias
• Michael Matthay, MD Allogeneic human mesenchymal stem cells for the treatment of human acute lung injury
• Synthia Mellon, PhD Neurosteroids as therapeutics for brain disorders
• Robert Messing, MD Discovery of a PKC epsilon-selective inhibitor to treat pain
• Mary Nakamura, MD Recombinant fusion proteins that redirect VEGF to actively kill cancer cells: R1FasL and R1TRAIL
• Douglas Nixon, MD, PhD Herv antibodies and breast cancer
• Mark Wilson, MD Catheter-directed tissue ablation in the interventional MRI environment
• Yvonne Wu, MD, MPH Neonatal erythropoietin in asphyxiated term infants
• Iwei Yeh, MD, PhD Droplet digital PCR detection of circulating melanoma DNA—detecting early metastasis and progression in the age of targeted therapy

 

2010 - Spring

• Connor Caffrey, PhD Rapid diagnostic tool for schistosome infection
• Laura Koth, MD Blood gene expression diagnosis of sarcoidosis
• Steve Miller, MD, PhD QC validation for Virochip microarray as a diagnostic
• Robert Nussbaum, MD Test of pharma inhib of alpha synuclein translation by posiphen

 

2010 - Fall

• Anthony Luke, MD Validation of the RunSafe: 2-Dimensional gait analysis method with gold standard 3-Dimensional biomechanical analysis
• Daniel Schwartz, MD Use of phase contrast OCT for imaging the human retinal vasculature
• Qizhi Tang, PhD Manufacturing donor-specific regulatory T cells