Small-molecule activation of the tumor suppressor kinase LKB1 via the pseudokinase STRAD.
Kretschmer LS, Mitchell DC, Liu J, Leak L, Turnham RE, Wang L, Wang Z, He C, Ding L, Adler M, Kellett T, Keith A, Hwang YC, Chan GKL, Gottschalk RLG, Li W, Chan LM, Ramamoorthi R, Lively S, Drakas RA, Ramani V, Qing T, Verba KA, Bivona T, Ostrem JML, Beresis RT, Gordan JD
Cell chemical biology, 2026