Tissue Repair Slows in Old Age. These Proteins Speed It Back Up
New research from UC San Francisco has found gene regulators that turn genes on and off that could restore the aging body’s ability to self-repair. The scientists looked at fibroblasts, cells found throughout the body that slow down due to aging, leading to wrinkles and poor healing.
“By altering gene expression using the transcription factors we identified, old fibroblasts behaved as if they were younger and improved the health of old mice,” said Hao Li, PhD, UCSF professor of Biochemistry and Biophysics
Congratulations to the UCSF team that worked on this technology, including Hao Li, PhD, Janine Sengstack, PhD, and Saul Villeda, PhD. Also, Jiashun Zheng, PhD, Turan Aghayev, MD, PhD, Gregor Bieri, PhD, Michael Mobaraki, PhD, Jue Lin, PhD, and Changhui Deng, PhD. for their contributions.